The Journal of Clinical Psychiatry and The Primary Care Companion for CNS Disorders are peer-reviewed leaders informing clinical practice and patient care.
In patients with depression, psychological pain is a risk factor for suicidal ideation. Those with borderline personality disorder may experience more prominent and temporally unstable psychological pain.
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A population pharmacokinetic simulation study, published in JCP, suggests paliperidone palmitate 351 mg given every 6 to 8 weeks could match blood levels of standard monthly dosing, though no clinical data yet support these alternative regimens. JCP → psychiatrist.com/jcp/pharmacoki…
A post hoc analysis of a phase 3, randomized, double-blind trial, published in JCP, examined adjunctive lumateperone 42 mg in patients with MDD and inadequate antidepressant response, comparing those with and without DSM-5-defined anxious distress. The authors describe the
A case vignette and discussion published in PCC describes psychological reactions to traumatic amputation, noting that the classic Kübler-Ross stages of grief often appear after limb loss, though not always in a fixed order.
Denial may show up as being unable to look at the
A study of the EPINET early-psychosis network, published in JCP, found that use of long-acting injectable antipsychotics ranged from 5% to 37.5% and clozapine use from 1.7% to 9.0% across 8 hubs, with even wider variation at the clinic level.
JCP → psychiatrist.com/jcp/long-actin…